A agentindex
Comparison

AutoGen vs Mastra

A like-for-like, spec-level comparison. Both entries are verified against their docs and repo.

AutoGen

Microsoft's framework for multi-agent conversations.

  • + Backed by Microsoft research
  • + Strong on conversational agent patterns
  • − API churned across major versions
  • − Heavier abstraction layer

Mastra

The TypeScript-first agent framework.

  • + Best-in-class DX for TS/JS teams
  • + Includes evals and memory out of the box
  • − Elastic license limits some commercial hosting
  • − Smaller community than Python options
Spec AutoGen Mastra
Category framework framework
License MIT Elastic-2.0
Open source Yes Yes
Self-hostable Yes Yes
MCP support Yes Yes
Pricing free free
Starting price BYOK usage cost BYOK usage cost
Models claude, gpt, gemini, byok claude, gpt, gemini, byok
Languages python, dotnet typescript
GitHub stars 59.2k 25.4k
Last activity 2026-04-15 2026-06-25