A agentindex
Comparison

AutoGen vs Letta

A like-for-like, spec-level comparison. Both entries are verified against their docs and repo.

AutoGen

Microsoft's framework for multi-agent conversations.

  • + Backed by Microsoft research
  • + Strong on conversational agent patterns
  • − API churned across major versions
  • − Heavier abstraction layer

Letta

Stateful agents with long-term memory (formerly MemGPT).

  • + First-class long-term memory and stateful agents
  • + Lets agents persist and self-edit context
  • − Narrower focus than general orchestration frameworks
  • − Memory model adds complexity
Spec AutoGen Letta
Role Agent framework Agent framework
Tags agent-framework, library, multi-agent, persona-solo-builder, persona-platform-engineer agent-framework, library, multi-agent, memory, persona-solo-builder, persona-platform-engineer
License MIT Apache-2.0
Open source Yes Yes
Self-hostable Yes Yes
MCP support Yes Yes
Pricing free freemium
Price Free Free tier
Usage cost BYOK BYOK
Models claude, gpt, gemini, byok claude, gpt, gemini, byok
Languages python, dotnet python
GitHub stars 59.5k 23.6k
Last activity 2026-04-15 2026-07-03