A agentindex
Comparison

Agno vs AutoGen

A like-for-like, spec-level comparison. Both entries are verified against their docs and repo.

Agno

A high-performance multi-agent framework and runtime (formerly Phidata).

  • + Built-in runtime, tracing, and management UI
  • + Strong on multi-modal, memory-heavy agents
  • − Broad surface area to learn
  • − Fast-moving after the Phidata rebrand

AutoGen

Microsoft's framework for multi-agent conversations.

  • + Backed by Microsoft research
  • + Strong on conversational agent patterns
  • − API churned across major versions
  • − Heavier abstraction layer
Spec Agno AutoGen
Role Agent framework Agent framework
Tags agent-framework, library, multi-agent agent-framework, library, multi-agent
License Apache-2.0 MIT
Open source Yes Yes
Self-hostable Yes Yes
MCP support Yes Yes
Pricing free free
Starting price BYOK usage cost BYOK usage cost
Models claude, gpt, gemini, byok claude, gpt, gemini, byok
Languages python python, dotnet
GitHub stars 40.9k 59.3k
Last activity 2026-06-26 2026-04-15